"Got Guts" The Micro Version: Inhibitory neurotransmission in the internal anal sphincter

Coauthor Caroline A. Cobine dives into the fascinating world of internal anal sphincter biology in the latest episode of "Gut Guts." The research uncovers direct and indirect neural pathways that modulate intracellular calcium activity in interstitial cells of Cajal, shedding light on their role in smooth muscle cell function.

 

Article Citation:

Modulation of intracellular calcium activity in interstitial cells of Cajal by inhibitory neural pathways within the internal anal sphincter

Karen I. Hannigan, Emer P. Ni Bhraonain, Thomas W. Gould, Kathleen D. Keef, and Caroline A. Cobine

American Journal of Physiology-Gastrointestinal and Liver Physiology 2024 327:3, G382-G404