”Got Guts” The Micro Version: Maternal influenza infection and offspring gut immunity

In this podcast lead author Dr. Stella Liong of RMIT University, discusses the recently published manuscript titled “Influenza A virus infection during pregnancy causes immunological changes in gut-associated lymphoid tissues of offspring mice.”

 

NEW & NOTEWORTHY Influenza A virus (IAV) infection during pregnancy is associated with changes in gut-associated lymphoid tissue (GALT) in the offspring in a region-dependent manner. Neutrophils and monocytes/macrophages were elevated in the cecal patch of offspring from infected dams. This increase in innate immune cell infiltration was not observed in the Peyer’s patches. T cells were also elevated in the cecal patch but not in the Peyer’s patches.

 

Article Citation:

Influenza A virus infection during pregnancy causes immunological changes in gut-associated lymphoid tissues of offspring mice

Stella Liong, Mark A. Miles, Mitra Mohsenipour, Felicia Liong, Elisa L. Hill-Yardin, and Stavros Selemidis

American Journal of Physiology-Gastrointestinal and Liver Physiology 2023 325:3, G230-G238